DSP-Associated Arrhythmogenic Cardiomyopathy Cases Presenting as Myocarditis

A case report and literature review summarizing clinical and genetic data from 22 patients with arrhythmogenic cardiomyopathy caused by DSP gene mutations. The data includes patient demographics, genetic variant details, troponin levels, electrocardiogram findings, and echocardiography results. The dataset was published on figshare by Xinyu Lin in May 2026 under a CC-BY-4.0 license.

Use Cases

• Identify common clinical presentations of DSP-associated ACM based on the described symptoms and imaging findings.
• Analyze the relationship between specific DSP gene mutations and cardiac phenotypes based on the reported genetic variants.
• Study the correlation between elevated troponin levels and disease progression in ACM based on the reported biomarker data.
• Review electrocardiogram and echocardiography abnormalities in pediatric and adult ACM cases based on the summarized clinical features.

Strengths

• Includes detailed genetic data on 22 identified patient cases with DSP gene mutations.
• Reports specific clinical measurements, including troponin levels for all patients and electrocardiogram findings for all cases.
• Documents a novel compound heterozygous variant (c.7964C>G and c.6785G>T) in the DSP gene.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 109.8 KB, indicating a limited scope focused on a specific case and literature review.

Provenance

Source

figshare, authored by Xinyu Lin.

Collection Method

Retrospective case analysis and literature review from databases including PubMed, Medline, Web of Science, China National Knowledge Infrastructure, and Wanfang Database.

Freshness

Last updated 2026-05-19 05:31:03; freshness should be verified.