Gestational Diabetes Adipokine Levels in Maternal and Cord Blood

A retrospective observational cohort study analyzed leptin, adiponectin, and soluble leptin receptor concentrations in maternal and cord blood plasma from 30 hyperglycemic and 23 normoglycemic pregnancies. The dataset includes derived indices such as the leptin-to-adiponectin ratio and free leptin index. The study was authored by Jolanta Lis‐Kuberka and shared under a CC-BY-4.0 license on figshare.

Use Cases

• Investigating links between maternal leptin levels and insulin treatment severity based on reported group comparisons.
• Analyzing associations between cord blood adiponectin and neonatal birth weight as described in the results.
• Studying leptin resistance indicators like the leptin-to-adiponectin ratio in gestational diabetes.
• Exploring metabolic programming risks across generations using the reported adipokine dysregulation.

Strengths

• Includes specific concentration values for key biomarkers (e.g., maternal leptin 10.05 ng/mL in GDM-insulin group).
• Compares distinct clinical groups: diet-controlled GDM, insulin-treated GDM, and normoglycemic pregnancies.
• Analyzes both maternal and fetal (cord blood) samples, providing a paired view of the maternal-fetal axis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small in scale (324.5 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Retrospective observational cohort study using immunoenzymatic assays on plasma samples.

Freshness

Last updated 2026-05-12 04:19:30; freshness should be verified.