Arabidopsis Amino Acid Toxicity and Glutamine Alleviation Data

A study by Lauren M. Kerwien, published on figshare in March 2026, establishes a framework for studying amino acid metabolic pathways in Arabidopsis. The research precisely determines the toxicity levels of individual amino acids on plant growth in solid and liquid media, with concentrations tested up to 20 mmol.l⁻¹. It investigates the alleviation of this toxicity by glutamine and the potential role of the Target of Rapamycin (TOR) signaling pathway.

Use Cases

• Modeling amino acid toxicity thresholds based on the reported concentration ranges (0.3-4 mM).
• Studying metabolic pathway feedback inhibition based on the described relief of toxicity by related amino acids.
• Investigating the role of glutamine in plant stress response based on its described alleviation of single amino acid toxicity.
• Analyzing the interaction between amino acid metabolism and TOR signaling based on experiments with the inhibitor AZD8055.

Strengths

• Data is associated with a peer-reviewed scientific study, providing experimental context.
• Specific toxicity concentration ranges (0.3-4 mM) and a high test limit (20 mmol.l⁻¹) are reported.
• The license is clearly defined as CC-BY-4.0, permitting reuse with attribution.

Limitations

• The primary data format is a 3.4 MB PDF, which likely contains textual and graphical results rather than structured, machine-readable data tables.
• Row and column counts for any underlying quantitative data are unknown, limiting suitability assessment for direct computational analysis.
• Column-level documentation is absent; field semantics must be inferred from the publication text.

Provenance

Source

figshare, authored by Lauren M. Kerwien.

Collection Method

Experimental data from growing Arabidopsis plants in controlled media with varying amino acid concentrations.

Freshness

Last updated 2026-03-19 06:49:54