Mithun Vaccine Immune Response Data from a 12-Month Field Study in Nagaland

Nagaland, India, was the site of a 12-month longitudinal field study assessing a heterologous goatpox vaccine in Mithun (Bos frontalis). The dataset includes humoral response data from ELISA and virus neutralization tests, as well as cytokine marker data from serum and PBMC mRNA profiling. It was authored by Gundallahalli Bayyappa Manjunatha Reddy and last updated in April 2026.

Use Cases

• Modeling antibody response kinetics based on ELISA and VNT data mentioned in the description
• Analyzing correlations between humoral and cytokine immune markers described in the study
• Evaluating vaccine safety and efficacy in a field setting for Mithun populations
• Establishing baseline immune parameters for future LSD control strategy development

Strengths

• Data is from a 12-month longitudinal field study, providing a time-series perspective.
• Includes multiple immune response measures: indirect ELISA, virus neutralization test, and cytokine profiling.
• The dataset is openly available under a CC-BY-4.0 license.

Limitations

• The dataset is small (279.8 KB), indicating limited scope or a summary document.
• Column-level documentation is absent; field semantics must be inferred after download.
• The study notes that antigen-specific cell-mediated immunity was not assessed.

Provenance

Source

figshare

Collection Method

Longitudinal field study involving sequential nasal swabs, serum, and PBMC samples.

Time Range

Study duration was 12 months.

Freshness

Last updated 2026-04-21 04:14:13; freshness should be verified.

Geography

Nagaland, Northeast India.