HARM and Thrombus Analysis in Acute Ischemic Stroke: 56 Patient Cohort

Sena Aksoy's dataset from 2026 contains clinical and histopathological data from 56 patients who underwent mechanical thrombectomy for acute ischemic stroke. It includes procedural data, recanalization scores, and 24-hour FLAIR imaging results to identify the Hyperintense Acute Reperfusion Marker (HARM). The dataset also comprises histopathological analysis of 52 retrieved thrombi, stained for fibrin, erythrocytes, and leukocytes, alongside 24-hour NIHSS and 90-day mRS clinical outcome scores.

Use Cases

• Predicting clinical outcomes (NIHSS/mRS scores) based on thrombus composition and HARM status.
• Analyzing the association between fibrin-rich thrombi and blood-brain barrier disruption indicated by HARM.
• Correlating procedural factors (number of passes, recanalization scores) with histopathological thrombus features.
• Training models to identify radiological markers (HARM on FLAIR) linked to specific thrombus characteristics.

Strengths

• Includes data from 56 patients with detailed procedural and clinical follow-up.
• Contains histopathological analysis of 52 retrieved thrombi with specific staining protocols documented.
• Clinical outcomes are measured with standardized scales (NIHSS at 24h, mRS at 90 days).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (251.4 KB), indicating limited scope.

Provenance

Source

Sena Aksoy via figshare

Collection Method

Clinical study of patients undergoing mechanical thrombectomy, with documented procedures, imaging, and laboratory thrombus analysis.

Freshness

Last updated 2026-03-19 15:00:34; freshness should be verified.