Data Sheet 1_Imaging photoplethysmography reveals differences in the reactions of cerebral

Anesthetized rats (n=10) were used to study cerebrovascular effects of vasoactive drugs. Synchronized video recordings of the cerebral cortex, electrocardiogram, systemic blood pressure, and end-tidal CO2 were collected. Alexey Y. Sokolov published the results on figshare in March 2026.

Use Cases

• Analyze the relationship between local vasomotor reactions and systemic hemodynamics based on amplitude of pulsatile component fluctuations.
• Investigate multiphasic cerebrovascular responses to vasodilators and vasoconstrictors based on the described stereotypical APC changes.
• Model intracranial hemodynamic shifts caused by adenosine triphosphate or norepinephrine based on the synchronized physiological monitoring.
• Validate imaging photoplethysmography as a quantitative marker of local vasodilation/vasoconstriction based on the experimental results.

Strengths

• Data includes synchronized recordings from four modalities: video, electrocardiogram, blood pressure, and end-tidal CO2.
• Experimental results are based on a sample of 10 anesthetized rats.
• The study specifically compares effects of two vasoactive agents: adenosine triphosphate and norepinephrine.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect the bias inherent to a specific rat model experimental setup.

Provenance

Source

figshare

Collection Method

Experimental study involving video recording and physiological monitoring of anesthetized, artificially ventilated rats.

Freshness

Last updated 2026-03-19 05:17:31; freshness should be verified.