Oral Cancer Surgery Outcomes for 692 Patients with Neoadjuvant Therapy

A retrospective cohort study of 692 patients with locally advanced oral squamous cell carcinoma undergoing curative-intent surgery. The data compares major wound complication rates and recovery metrics across three treatment cohorts: neoadjuvant immunochemotherapy, neoadjuvant chemotherapy, and upfront surgery. The dataset was authored by Hongli Chen and last updated on March 18, 2026.

Use Cases

• Compare major wound complication rates based on treatment cohort (neoadjuvant immunochemotherapy vs. chemotherapy vs. upfront surgery).
• Model time to complete wound sealing using adjusted hazard ratios reported in the study.
• Identify independent risk factors for complications within the neoadjuvant immunochemotherapy cohort, such as pathological response or smoking history.
• Analyze the impact of treatment on secondary endpoints like length of hospital stay and time to adjuvant radiotherapy.

Strengths

• Includes data for 692 patients, providing a substantial cohort for analysis.
• Reports specific, statistically significant findings, such as a major wound complication rate of 9.2% in the immunochemotherapy cohort.
• Contains multivariable analysis results, including adjusted odds ratios and hazard ratios for key outcomes.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset is very small (40.0 KB), indicating limited scope, likely containing summary results rather than raw patient-level data.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

figshare, authored by Hongli Chen.

Collection Method

Retrospective cohort study.

Freshness

Last updated 2026-03-18 07:36:29; freshness should be verified.