Single-Cell TCR and BCR Repertoire Data from Malignant Pleural Effusion

A 1018.8 KB PDF document authored by Chuang-Xin Zhang and last updated on 2026-04-28. This research data sheet presents a single-cell atlas of T-cell and B-cell receptor repertoires from malignant pleural effusion and peripheral blood samples in lung adenocarcinoma patients.

Use Cases

• Characterizing clonal expansion of Th1/17 cells based on single-cell V(D)J sequencing data
• Analyzing functional heterogeneity in cytotoxic CD8+ T cells based on exhaustion and cytotoxicity signatures
• Investigating antigen recognition patterns based on TCR complementary determining region 3 features
• Comparing adaptive immune cell profiles between malignant pleural effusion and blood samples

Strengths

• Data is derived from single-cell RNA sequencing and V(D)J sequencing, providing high-resolution immune profiles
• Includes paired malignant pleural effusion and peripheral blood samples for comparative analysis
• Released under a CC-BY-4.0 license, permitting broad reuse

Limitations

• Dataset is a 1018.8 KB PDF; the underlying raw sequencing data files are not directly accessible
• Column-level documentation is absent; field semantics must be inferred from the publication
• Row count is unknown, which may limit suitability assessment for computational analysis

Provenance

Source

figshare

Collection Method

Single-cell RNA sequencing and single-cell V(D)J sequencing of human lung adenocarcinoma-associated malignant pleural effusion and peripheral blood samples

Time Range

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Freshness

Last updated 2026-04-28 04:28:31

Geography

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