iMOSS: High-Resolution Rodent Immobility Scores Synchronized with Neural Activity

An open-source dataset and toolset for the tail suspension test, a behavioral assay for stress-coping in rodents. The dataset includes high-resolution immobility and mobility scores generated by two complementary tools, iMOSS-MV and iMOSS-AS, which are designed for seamless integration with neural recording data. The data was authored by Zengyou Ye and last updated on May 8, 2026.

Use Cases

• Screen antidepressant compounds based on changes in immobility bouts detected by the platform.
• Correlate neural calcium activity with behavioral states based on the described synchronization capability.
• Benchmark automated behavioral scoring tools against manual frame-by-frame annotations.
• Study stress-coping behavior in rodents based on high-resolution quantification of active and passive responses.

Strengths

• Data is generated by two validated tools, with iMOSS-AS output closely matching manual scoring from iMOSS-MV.
• The platform demonstrated sensitivity to pharmacological manipulation, detecting changes induced by imipramine treatment.
• Released under a permissive CC-BY-4.0 license, facilitating open reuse and modification.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.
• The primary file format is a 1.4 MB PDF, which may require extraction to access structured data.

Provenance

Source

figshare

Collection Method

Data generated using the iMOSS open-source tools for video-based manual scoring and sensor-based automated detection.

Time Range

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Freshness

Last updated 2026-05-08 05:54:19; freshness should be verified.

Geography

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