Drosophila Immune Response Data Under High-Sucrose Diet and AITC Supplementation

A 1.0 MB dataset by Sonja Dähn, last updated April 2026, investigates the impact of allyl-isothiocyanate on host defense in fruit flies fed a high-sugar diet. The study includes qPCR and RNA sequencing data on antimicrobial peptide expression and lifespan analysis following infection with two specific bacterial pathogens. Results indicate the effects are strongly sex-specific and AITC did not enhance host defense under these conditions.

Use Cases

• Modeling sex-specific immune responses based on survival data following bacterial infection.
• Analyzing transcriptional changes in antimicrobial peptides like Attacin D under different dietary conditions.
• Studying the interaction between metabolic stress (high-sucrose diet) and immune pathway (Toll/Imd) activation.
• Investigating the in vivo effects of plant-derived compounds (isothiocyanates) on host protection.

Strengths

• Data is associated with a detailed experimental study published on figshare.
• Includes analysis of two distinct bacterial pathogens targeting specific immune pathways.
• Released under a permissive CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data format is PDF, which may require extraction for computational analysis.

Provenance

Source

Sonja Dähn via figshare.

Collection Method

Experimental data from Drosophila melanogaster studies involving dietary manipulation, bacterial infection, and molecular analysis.

Time Range

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Freshness

Last updated 2026-04-10 05:58:16; freshness should be verified.

Geography

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