Impact of TriGUARD 3 on Cerebral Protection in Chinese TAVR Patients

Data from a study evaluating the TriGUARD 3 cerebral embolic protection device in Chinese patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. The dataset includes 118 participants (62 in the CEPD group, 56 controls) assessed via pre- and post-operative diffusion-weighted magnetic resonance imaging. It was authored by Yan Li and last updated on 2026-03-18.

Use Cases

• Compare total cerebral ischemic lesion volumes based on device usage and patient subgroups.
• Analyze the association between embolic protection and lesion metrics in patients with bicuspid aortic valve stenosis.
• Investigate the impact of covariates like age, sex, and hypertension on lesion outcomes using median regression.

Strengths

• Includes data from 118 patients across a multicenter trial and a single-center registry.
• Reports specific lesion volume metrics (total, average, maximum) with interquartile ranges and p-values.
• Analyzes a distinct patient subgroup (bicuspid aortic valve stenosis) with statistically significant findings.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.
• Data may reflect geographic bias inherent to the Chinese patient cohort.

Provenance

Source

Yan Li via figshare.

Collection Method

Data pooled from a multicenter TG3 trial (CEPD group) and a single-center registry (control group).

Freshness

Last updated 2026-03-18 06:42:10; freshness should be verified.

Geography

China