Systematic Review and Meta-Analysis of EIT-Guided vs Fixed PEEP in Laparoscopic Surgery

A systematic review and meta-analysis of five randomized controlled trials (n=290) evaluating individualized positive end-expiratory pressure (PEEP) guided by electrical impedance tomography versus fixed PEEP in laparoscopic surgery. The analysis, conducted by Abdelrhman H. Mohamed and registered in PROSPERO (CRD420251169858), was published on figshare in May 2026. It synthesizes evidence on outcomes including postoperative atelectasis, oxygenation, and perioperative hemodynamics.

Use Cases

• Compare the efficacy of individualized versus fixed PEEP strategies based on the meta-analysis of clinical trial outcomes.
• Assess the impact of EIT-guided PEEP on postoperative atelectasis based on lung ultrasound findings.
• Evaluate the effect of ventilation strategies on perioperative oxygenation based on PaO₂/FiO₂ ratio data.
• Investigate the association between recruitment maneuvers and hemodynamic complications like bradycardia based on reported adverse events.

Strengths

• Follows PRISMA guidelines and was prospectively registered in PROSPERO, indicating a structured methodology.
• Includes sensitivity analyses (leave-one-out) to evaluate the robustness of the meta-analysis results.
• Synthesizes data from five randomized controlled trials using a random-effects model.

Limitations

• The underlying dataset consists of a single PDF document; column-level data and raw trial data are not provided.
• The analysis is based on a relatively small pooled sample size of 290 patients from five trials.
• Row count and granular data structure are unknown, limiting direct reuse for secondary analysis.

Provenance

Source

figshare, authored by Abdelrhman H. Mohamed.

Collection Method

Systematic review and meta-analysis of published randomized controlled trials.

Freshness

Last updated 2026-05-15.