Meta-Analysis of Vitamin D Supplementation and Ovarian Reserve in 992 Women

Eleven randomized controlled trials with 992 women were included in this meta-analysis evaluating the influence of vitamin D supplementation on ovarian reserve, measured by serum anti-Müllerian hormone (AMH) levels. The pooled analysis found no significant overall effect, with substantial heterogeneity noted. The dataset was authored by Sitian Fang and uploaded to figshare in May 2026.

Use Cases

• Assessing the overall effect of vitamin D supplementation on AMH levels based on pooled data from 11 RCTs.
• Investigating heterogeneity in trial outcomes based on study design, such as double-blind versus open-label trials.
• Examining subgroup effects based on baseline AMH levels, where a reduction was observed in studies with AMH > 6 ng/mL.
• Evaluating the influence of factors like age, baseline vitamin D status, dose, and treatment duration on the primary outcome.

Strengths

• Includes data from 11 randomized controlled trials, a standard for clinical evidence.
• Analyzes results from 992 women, providing a substantial sample size for a meta-analysis.
• Employs a random-effects model to account for potential heterogeneity across studies.
• Conducts multiple subgroup analyses based on trial design and patient characteristics.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is a 665.6 KB DOCX file, suggesting it is a document containing the analysis rather than a raw data table.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials sourced from PubMed, Cochrane Library, Embase, Web of Science, Wanfang, and CNKI.

Freshness

Last updated 2026-05-11 04:20:42; freshness should be verified.