CD99 Ligand Interaction Effects on NK Cell Receptor Modulation

A study investigating the immunoregulatory role of CD99 in natural killer cells. Myint Myat Thu authored this research, which analyzes flow cytometry data from peripheral blood mononuclear cells and purified NK cells stimulated with interleukin-2. The dataset was last updated on June 4, 2026.

Use Cases

• Modeling NK cell activation states based on receptor expression changes described in the study.
• Comparing immunomodulatory responses between mixed PBMC cultures and purified NK cells as described.
• Investigating the context-dependent regulation of natural cytotoxicity receptors (NCRs) via CD99 engagement.

Strengths

• The dataset is associated with a specific, peer-reviewed research question on CD99 and NK cell modulation.
• It includes comparative analysis between two sample types: PBMCs and purified NK cells.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The data is contained in a 2.6 MB DOCX file, which may require extraction of structured data.

Provenance

Source

figshare

Collection Method

Flow cytometric analysis of PBMCs and purified NK cells following stimulation with IL-2 and CD99 fusion protein.

Freshness

Last updated 2026-06-04 05:39:59; freshness should be verified.