Immune Profiling Data for Cervical Tuberculous Lymphadenitis Patients

Integrated immune profiling data from a study of 60 patients with cervical tuberculous lymphadenitis (CTL) and 44 control patients with non-tuberculous lymphadenopathy. The dataset includes qPCR measurements of immune-gene expression from peripheral blood and lymph node cells, serum IL-15 ELISA results, and immunohistochemistry findings. It was authored by Soumala Bchiri and last updated on June 3, 2026.

Use Cases

• Identify hub cytokines within cytotoxic immune networks based on correlation-network analysis described in the study.
• Correlate serum IL-15 levels with bacillary burden in tuberculosis patients, as indicated by the GeneXpert-defined metric.
• Analyze co-expression patterns of cytotoxic effector genes like granulysin, granzyme B, and perforin.
• Investigate macrophage-mediated IL-15 trans-presentation within granulomatous tissue using immunohistochemistry data.

Strengths

• Includes data from a well-defined cohort of 60 CTL patients and 44 control patients.
• Provides multi-compartment data with measurements from both peripheral blood and lymph node cells.
• Employs multiple analytical methods: qPCR, ELISA, immunohistochemistry, and systems-level network analysis.

Limitations

• The dataset is very small at 10.8 KB, suggesting limited raw data or summary-level results.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.

Provenance

Source

figshare

Collection Method

Clinical study involving immune profiling via qPCR, ELISA, and immunohistochemistry.

Freshness

Last updated 2026-06-03 04:47:34; freshness should be verified.