Data Sheet 1_Investigating the therapeutic mechanism of Puerarin in vascular dementia: an

Experimental data from a study investigating the therapeutic mechanism of Puerarin in vascular dementia. The dataset likely contains results from behavioral testing, histological staining, network pharmacology analysis, and molecular assays. The data was authored by Hongmei Tang and last updated on April 29, 2026.

Use Cases

• Validate network pharmacology predictions based on identified overlapping targets between Puerarin and vascular dementia.
• Analyze behavioral and histological outcomes based on cognitive performance and neuronal morphology assessments.
• Model signaling pathway involvement based on enrichment analyses of Toll-like receptor and NF-κB pathways.
• Correlate molecular expression levels based on TLR4, MyD88, and NF-κB p65 phosphorylation data.

Strengths

• The dataset integrates multiple experimental methods, including behavioral testing, histology, network pharmacology, and molecular assays.
• The study includes validation using a TLR4 agonist to counteract therapeutic effects, providing a control mechanism.
• The dataset is licensed under CC-BY-4.0, allowing for open reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Hongmei Tang

Collection Method

Data generated from behavioral tests, histological staining, network pharmacology analysis, and experimental validation assays.

Freshness

Last updated 2026-04-29 05:37:30; freshness should be verified.