Isoflurane Sedation Data for Critically Ill Children, 2017–2020

A retrospective observational study from 2017–2020 at a single-center, 10-bed tertiary pediatric intensive care unit. It analyzes 21 mechanically ventilated children who received inhaled isoflurane as rescue sedation after conventional regimens failed. The dataset was authored by Richard Biedermann and shared under a CC-BY-4.0 license.

Use Cases

• Analyzing the impact of rescue sedation on sedative polypharmacy based on the reported reduction in median number of sedative agents.
• Modeling the relationship between volatile anesthetic use and hemodynamic support based on changes in the vasoactive-inotropic score.
• Studying post-sedation outcomes like delirium and withdrawal rates mentioned in the survivor population.
• Evaluating the efficacy of sedation strategies based on the reported decline in rescue medication use for breakthrough agitation.

Strengths

• Includes data for 21 pediatric patients with detailed clinical metrics.
• Covers a defined time range from 2017 to 2020 in a specific 10-bed PICU setting.
• Reports specific statistical outcomes, such as a reduction in rescue medication use from 100% to 42.9%.

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Single-center retrospective observational study.

Time Range

2017–2020

Freshness

Last updated 2026-05-28 05:57:43; freshness should be verified.

Geography

Data likely originates from a single tertiary pediatric intensive care unit; specific location is unknown.