Genome Sequence of a Novel Duck Hepatitis A Virus Strain from China

HNAY2024, a potentially novel Duck Hepatitis A Virus type 3 strain, was isolated from a vaccinated duck flock in Henan Province, China. The dataset contains the complete genome sequence, with phylogenetic analysis showing 91.9%–99.9% nucleotide identity to reference strains and identification of eight amino acid substitutions in the VP1 gene.

Use Cases

• Perform phylogenetic analysis using the complete genome sequence to compare HNAY2024 against reference strains like ZU-ARMY-DHA-36.
• Analyze the eight identified amino acid substitutions (V413M, E683Q, etc.) in the VP1 gene to predict impacts on viral antigenicity and host interactions.
• Study the vaccine-escape potential of the HNAY2024 strain by examining its genetic divergence from classical DHAV-3 patterns.
• Map the potential geographical dissemination of the virus by comparing its sequence to strains from Egypt, Henan, and Shandong.

Strengths

• Contains the complete genome sequence of a novel viral strain with identified vaccine-escape potential.
• Phylogenetic analysis provides specific nucleotide identity percentages (91.9%–99.9%) against reference strains.
• Identifies eight specific amino acid mutation sites in the VP1 gene for targeted analysis.

Limitations

• Dataset is a single 144.1 KB PDF document, not a structured tabular dataset, limiting computational analysis.
• Scope is limited to one isolated strain (HNAY2024); lacks comparative data from a large sample of other strains.
• No raw sequencing reads or structured genomic feature tables are provided, only analysis results.

Provenance

Source

Yuqing Dan via figshare.

Collection Method

Virus isolation, purification, whole-genome sequencing, and phylogenetic analysis.

Time Range

Isolation date unspecified; study likely contemporary.

Freshness

Last updated March 2026.

Geography

Henan Province, China.