Isorhamnetin Effects on 4T1 Breast Cancer Cells: Experimental Results

Fei Chen published a research data sheet on figshare in May 2026. The document describes experimental results investigating the antitumor effects of Isorhamnetin on mouse breast cancer 4T1 cells. The study includes data on cell viability, migration, apoptosis, oxidative stress, mitochondrial function, and TIGIT/CD155 signaling.

Use Cases

• Analyze concentration-dependent effects on cell proliferation based on CCK-8 assay results.
• Study the relationship between oxidative stress and apoptosis based on ROS and mitochondrial membrane potential measurements.
• Investigate the role of the TIGIT/CD155 signaling axis in cancer cell migration based on Western blot and qPCR data.
• Compare clonogenic capacity under different treatments based on colony formation assay results.

Strengths

• The dataset is licensed under CC-BY-4.0, allowing for open reuse.
• The description provides detailed methodological context for the experimental data.

Limitations

• The dataset is a 6.6 MB DOCX file; the underlying data structure and column-level documentation are absent.
• Row count is unknown, which may limit suitability assessment.
• Last updated 2026-05-07 04:37:10; freshness should be verified.

Provenance

Source

Fei Chen

Collection Method

Experimental data from cell viability, wound healing, colony formation, ROS measurement, mitochondrial membrane potential, qPCR, and Western blot assays.

Freshness

Last updated 2026-05-07 04:37:10