Data Sheet 1_KpFhaB/FhaC: A Virulence-Associated TPS System in Klebsiella pneumoniae ST15

Ana Tajuelo authored a research data sheet describing the KpFhaB/FhaC two-partner secretion system in the Klebsiella pneumoniae ST15 high-risk clone. The document, last updated in June 2026, details genomic analyses and functional studies on biofilm formation, epithelial cell adhesion, and bacterial fitness. The dataset is a 976.5 KB DOCX file shared under a CC-BY-4.0 license on figshare.

Use Cases

• Study the role of the KpFhaB/FhaC TPS system in bacterial adhesion based on the described functional characterization.
• Investigate complementary virulence mechanisms between TPS and chaperone-usher pili systems based on the described additive phenotype reduction.
• Analyze genomic conservation of virulence factors within the K. pneumoniae ST15 high-risk clone based on the described bioinformatic analysis.
• Model bacterial fitness costs associated with virulence factor inactivation based on the described experimental results.

Strengths

• The dataset is associated with a specific, globally significant bacterial clone (K. pneumoniae ST15).
• The description provides detailed methodological context including genomic analysis and in vitro/in vivo models.
• The data sheet is openly licensed (CC-BY-4.0) for reuse.

Limitations

• The dataset is a single 976.5 KB DOCX file, indicating a very limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Ana Tajuelo

Collection Method

Genomic and bioinformatic analyses, knockout strain construction, and functional studies (biofilm formation, adhesion, fitness, colonization assays).

Freshness

Last updated 2026-06-03 05:40:07; freshness should be verified.