Laminaria Japonica Polysaccharide Effects on Cerebral Ischemia-Reperfusion Injury

A 10.5 MB dataset from figshare, authored by Tangming Guan and last updated in April 2026. It contains research data on the neuroprotective effects of a marine-derived polysaccharide in a mouse model of stroke, including structural characterization, infarct volume, neurological function, and transcriptomic analysis.

Use Cases

• Modeling the anti-inflammatory effects of sulfated polysaccharides based on structural characterization data.
• Analyzing transcriptomic pathways in cerebral ischemia-reperfusion injury based on cross-species analysis results.
• Validating Csf3/G-CSF as a therapeutic target based on in vivo and in vitro functional assay data.

Strengths

• Includes multi-modal data: structural characterization (HPGPC, FT-IR), in vivo model outcomes, and transcriptomic analysis.
• Dataset is licensed under CC-BY-4.0, permitting open reuse with attribution.
• Research methodology is described in detail, including mouse tMCAO model and rescue experiments.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale ML tasks.
• Data is from a single, specific experimental study, which may limit generalizability.

Provenance

Source

figshare, author Tangming Guan.

Collection Method

Experimental research involving polysaccharide isolation, mouse model (tMCAO), and transcriptomic/functional assays.

Time Range

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Freshness

Last updated 2026-04 23 04:20:25; freshness should be verified.

Geography

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