A 5.8 KB CSV file containing data from a study on macrophage-related genes in idiopathic pulmonary fibrosis (IPF). The dataset, authored by Yuechong Xia and last updated in April 2026, likely includes results from single-cell transcriptomic and microarray analyses of patient samples from the GEO database. It focuses on the gene LGMN and its role in macrophage-fibroblast crosstalk.
Use Cases
- Developing prognostic gene signatures for IPF patients based on macrophage-related gene expression.
- Analyzing cell-cell interaction patterns, particularly between macrophages and fibroblasts, using inferred interaction data.
- Investigating the role of the TGF-β1 signaling pathway in fibrosis progression.
- Validating potential therapeutic targets, such as LGMN inhibition, using associated experimental results.
Strengths
- Data is derived from single-cell transcriptomic and microarray analyses, suggesting high-resolution biological detail.
- Includes validation via an external dataset and ROC curves, indicating methodological rigor.
- Published under a permissive CC-BY-4.0 license for reuse.
Limitations
- Row count and column-level documentation are unknown, limiting suitability assessment.
- The dataset is very small at 5.8 KB, indicating limited scope, likely containing summary or processed results rather than raw data.
- Description metadata is limited; actual data structure and semantics must be inferred after download.
Provenance
- Source
- figshare, author Yuechong Xia.
- Collection Method
- Analyzed single-cell transcriptomic and microarray data from the GEO database; bioinformatics and in vitro/vivo experiments.
- Time Range
- null
- Freshness
- Last updated 2026-04-13 04:35:54.
- Geography
- null