Liubao Tea Multi-Omics Data on Lymphatic Endothelial Cell Metabolism

A research document from figshare, authored by Xiaoxiao Huang and last updated in May 2026, details a multi-omics study on Liubao tea. The study combines single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking to investigate the tea's effects on human lymphatic endothelial cell function. In vitro validation experiments, including CCK-8 and RT-qPCR assays, are described.

Use Cases

• Identifying potential therapeutic targets for lymphedema based on the PRKCB gene and its interaction network.
• Validating multi-omics integration pipelines using the described workflow of single-cell, bulk transcriptome, and network pharmacology analysis.
• Screening natural product compounds for molecular docking studies based on the reported binding affinities to PRKCB.
• Designing in vitro experiments to test functional food extracts on cell survival and migration, as modeled by the described HLEC assays.

Strengths

• The study integrates multiple analysis methods, including single-cell transcriptomics and network pharmacology.
• Specific statistical results are reported, such as a fold change of 24.30 for PRKCB expression.
• In vitro validation with p-values (e.g., p < 0.001) is included for key findings.

Limitations

• The primary data file is a 894.0 KB DOCX document, which likely contains a manuscript rather than raw, reusable datasets.
• Column-level documentation for any underlying data tables is absent; field semantics must be inferred after download.
• Row count for any potential tabular data is unknown, which may limit suitability assessment.

Provenance

Source

figshare, author Xiaoxiao Huang.

Collection Method

Combined computational multi-omics analysis with in vitro cell culture experiments.

Freshness

Last updated 2026-05-18 05:38:41; freshness should be verified.