Long-term Cardio-metabolic Effects of Lifestyle Intervention in Obese Arab Women

201 obese, non-diabetic Arab women aged 35–54 participated in a randomized trial comparing intensive versus moderate lifestyle interventions. The dataset tracks cardio-metabolic risk factors over a median 12-year follow-up period after the intervention ended. It was created by Ofra Kalter-Leibovici from a trial conducted between 2006 and 2008.

Use Cases

• Analyze BMI trajectory differences between intensive and moderate intervention groups over the 12-year follow-up.
• Model the hazard ratios for achieving a BMI <30.0 kg/m² over time based on intervention type and baseline characteristics.
• Compare glucose trajectory outcomes for participants with impaired versus normal fasting plasma glucose levels at baseline.
• Assess long-term effects on blood pressure and plasma lipid levels following the lifestyle intervention withdrawal.

Strengths

• 201 participant records from a randomized controlled trial provide a structured cohort.
• Median follow-up duration of 12 years offers long-term longitudinal data on intervention effects.
• Data includes specific hazard ratios with confidence intervals for key outcomes like BMI reduction.

Limitations

• The dataset is small, with only 201 participants, limiting statistical power for subgroup analyses.
• Focus on a specific demographic (Arab women aged 35-54) limits generalizability to other populations.
• Data is presented in a DOCX document, requiring manual extraction for quantitative analysis.

Provenance

Source

Long-term follow-up of a randomized controlled trial conducted in a primary care setting.

Collection Method

Clinical trial with participants randomly assigned to intensive or moderate lifestyle intervention groups, with measurements taken during and after the trial.

Time Range

Trial conducted 2006-2008, with a median follow-up of 12 years post-intervention.

Freshness

Data reflects a trial from 2006-2008 with follow-up through approximately 2020, last updated in the repository in 2026.

Geography

Study conducted among Arab women, location unspecified but likely in a relevant primary care setting.