Systematic Review and Meta-Analysis on Neurodevelopment in Preterm NEC Survivors

A 2026 systematic review and meta-analysis by Katrien Vandenberghe examines long-term neurodevelopmental outcomes in preterm infants surviving necrotizing enterocolitis. The study, registered with PROSPERO, synthesizes evidence from PubMed, Embase, and Web of Science. It reports increased risks of impairment in motor skills, cognition, vision, hearing, and cerebral palsy for NEC survivors.

Use Cases

• Assessing the risk of neurodevelopmental impairment based on gestational age stratification mentioned in the description
• Comparing the impact of NEC on specific developmental domains like motor skills and cognition
• Informing long-term follow-up protocols for preterm infants based on the elevated risk findings

Strengths

• Follows PRISMA guidelines and uses GRADE and ROBINS-E tools for quality and bias assessment
• Includes gestational-age stratified subgroup analyses (22–28 weeks versus 29–34 weeks)
• Reports specific risk ratios with confidence intervals for multiple neurodevelopmental domains

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published literature from PubMed (including MEDLINE), Embase, and Web of Science.

Freshness

Last updated 2026-05-11 13:53:30