Noggin Protein Expression and Motor Function Data After Spinal Cord Injury in Mice

A research article investigating the role of the Noggin protein in glial scar formation and motor recovery following spinal cord injury in mice. The study uses conditional knockout mice and local antibody administration to examine GFAP expression and functional outcomes. The dataset is a 11.2 MB PDF file authored by Yibo Han and last updated on 2026-05-28.

Use Cases

• Analyze the relationship between Noggin expression and reactive astrogliosis based on the described experimental results.
• Study the effects of Noggin suppression on glial fibrillary acidic protein (GFAP) expression based on the conditional knockout and antibody treatment methods.
• Investigate the correlation between glial scar attenuation and motor function recovery based on the functional assessments described.
• Model the protective versus detrimental roles of specific proteins in spinal cord injury based on the findings regarding Noggin-mediated astrogliosis.

Strengths

• Data is associated with a detailed experimental methodology described in the article, including conditional knockout mice and localized antibody treatment.
• The dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
• The file size is 11.2 MB, indicating a document of substantial detail.

Limitations

• The core data is presented in a PDF document, requiring extraction for computational analysis.
• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset's primary content is a single research article, which may limit its scale for direct machine learning applications.

Provenance

Source

figshare

Collection Method

Experimental research involving mouse models of spinal cord injury, immunohistochemistry, and behavioral analysis.

Freshness

Last updated 2026-05-28 05:30:20; freshness should be verified.