Maternal Vitamin Levels and Infant Birth Weight in a Pregnancy Trial

A secondary analysis of the Exercise Training in Pregnancy Trial (ETIP) study includes 57 mother-infant pairs with overweight or obesity. Plasma retinol, α-tocopherol, and serum 25(OH)D concentrations were measured in the second and third trimesters and analyzed against infant birth weight. The dataset was authored by Astrid Kamilla Stunes and last updated on April 15, 2026.

Use Cases

• Analyze longitudinal changes in maternal vitamin A, D, and E levels based on trimester measurements.
• Investigate associations between maternal vitamin status and infant birth weight categories (normal vs. macrosomic).
• Model the prevalence of vitamin insufficiency/deficiency in a pregnant population with overweight or obesity.
• Examine potential interaction effects between different fat-soluble vitamins on fetal growth outcomes.

Strengths

• Includes specific mean and standard deviation values for vitamin concentrations across trimesters (e.g., retinol declined from 1.52 to 1.32 µmol/L).
• Reports precise prevalence statistics for clinical conditions (e.g., 43.9% macrosomia, 31.6% vitamin D deficiency).
• Data originates from a defined clinical trial (ETIP) with a clear methodology for vitamin measurement (HPLC, LC-MS/MS).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (71.3 KB), indicating a limited sample size of 57 pairs.

Provenance

Source

Secondary analysis of the Exercise Training in Pregnancy Trial (ETIP) study.

Collection Method

Plasma and serum samples analyzed via high performance liquid chromatography and liquid chromatography-tandem mass spectrometry.

Time Range

Measurements taken during the second and third trimesters of pregnancy.

Freshness

Last updated 2026-04-15 04:37:06; freshness should be verified.

Geography

Geographic coverage of the underlying trial is not specified in the provided description.