Mechanism of Periocular Acupuncture for Dry Eye Pain in Guinea Pig Model

Experimental data from a study investigating the neural pathway of periocular acupuncture for dry eye neuropathic pain. The dataset includes measurements from a guinea pig model, neural tracing results, and patch-clamp recordings. It was authored by Xinchen Wu and last updated on 2026-05-05.

Use Cases

• Analyze the therapeutic effect of acupuncture based on dry eye-related parameters and ocular surface sensitivity indicators.
• Study neural pathway specificity based on neural tracing results comparing acupoint and non-acupoint groups.
• Investigate neuronal hyperexcitability based on patch-clamp recordings of ventral posteromedial thalamic nucleus neurons.
• Correlate histopathological changes with treatment outcomes based on staining and microscopy data.

Strengths

• Dataset is 27.7 MB in size, facilitating download and local analysis.
• License is CC-BY-4.0, permitting broad reuse and sharing.
• Description details specific experimental methods, including neural tracing and patch-clamp recordings.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from an animal model (guinea pigs), which may limit direct applicability to human clinical research.

Provenance

Source

figshare

Collection Method

Data generated from a controlled laboratory experiment using a guinea pig model of dry eye neuropathic pain.

Freshness

Last updated 2026-05-05 05:28:49; freshness should be verified.