Clinical Trial Data on Moxibustion for Rheumatoid Arthritis via Wnt Pathway

A clinical trial dataset from a study of 70 rheumatoid arthritis patients investigating the effects of moxibustion combined with western medication. The dataset likely contains clinical symptom scores and serum biomarker levels for TNF-α, IL-17A, WNT3A, LRP-6, GSK-3β, β-catenin, OPG, and β-CTX. The study was authored by Hui Wang and shared on figshare.

Use Cases

• Analyze the correlation between Wnt pathway molecule changes and inflammatory markers based on serum levels of TNF-α and WNT3A.
• Compare clinical symptom improvement between treatment groups based on the described randomized controlled trial design.
• Model the relationship between bone resorption marker β-CTX and bone protective factor OPG based on the measured serum levels.
• Investigate the multi-target therapeutic effect on inflammation and bone metabolism based on the described mechanism involving TNF-α, IL-17A, OPG, and β-CTX.

Strengths

• Dataset is derived from a randomized controlled trial with 70 patients split into two groups of 35.
• Study measured multiple specific serum biomarkers, including TNF-α, IL-17A, WNT3A, LRP-6, GSK-3β, β-catenin, OPG, and β-CTX.
• Results include intra- and intergroup statistical comparisons with reported P-values.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is stored as a PDF (121.7 KB), which may not be in a readily analyzable tabular format.

Provenance

Source

figshare

Collection Method

Randomized controlled clinical trial.

Freshness

Last updated 2026-05-22 04:27:55; freshness should be verified.