Serum Metabolite Profiles for Pediatric Airway Allergic Diseases

Data Sheet 1_Metabolomics discover distinct metabolite profiles in children with different airway allergic diseases.pdf contains metabolomics data from a study of 194 pediatric patients. The study, authored by Yida Zhang and last updated in May 2026, analyzed serum carboxyl-containing metabolites from children with allergic rhinitis, asthma, and their combined syndrome using liquid chromatography-mass spectrometry.

Use Cases

• Identify disease-specific metabolic biomarkers based on the 23, 17, and 31 unique metabolites reported for AR, asthma, and CARAS.
• Investigate shared metabolic pathways based on the 100 differentially expressed metabolites common across the three conditions.
• Develop diagnostic models to differentiate allergic airway diseases based on the distinct metabolite profiles described.
• Explore links between immune dysregulation, gut dysbiosis, and metabolic disturbances suggested by the study findings.

Strengths

• Includes data from 194 pediatric patients (63 AR, 41 asthma, 90 CARAS), providing a defined clinical cohort.
• Identifies a specific number of metabolites: 100 common across diseases and 71 disease-specific.
• Data generated using a specific analytical method: ultra-high-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is presented in a PDF format (3.3 MB), which may require extraction to a structured format for analysis.

Provenance

Source

Yida Zhang via figshare

Collection Method

Ultra-high-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry analysis of serum samples.

Time Range

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Freshness

Last updated 2026-05-04 05:31:57; freshness should be verified.

Geography

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