Oral Microbiome Metagenomic Profiles from Diabetic and Non-Diabetic Periodontal Disease

Shotgun metagenomic analysis of subgingival plaque samples from 16 individuals across healthy, periodontitis, and diabetic periodontitis groups. The dataset includes results on alpha/beta diversity, taxonomic profiling, pathogen-probiotic ratios, and metabolic pathway abundance. It was authored by Harshvardhan and last updated on 2026-04 14.

Use Cases

• Classifying periodontal disease stages based on described microbial community structure and alpha diversity.
• Predicting metabolic status (e.g., diabetic periodontitis) based on described shifts in lipid metabolism and glycolysis pathways.
• Identifying potential probiotic or pathogenic bacterial markers from the described taxonomic profiles and pathogen-probiotic ratios.
• Modeling functional interactions in the oral microbiome using the described abundance of biosynthetic and degradative metabolic pathways.

Strengths

• Data is derived from a controlled pilot study with 16 individuals across four distinct clinical groups.
• Analysis includes multiple dimensions: taxonomic profiling, diversity metrics, and functional pathway abundance.
• License is CC-BY-4.0, permitting reuse with attribution.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The dataset is small at 2.4 MB, which may constrain statistical power for machine learning.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

figshare

Collection Method

Shotgun metagenomic analysis performed on pooled DNA from subgingival dental plaque samples.

Time Range

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Freshness

Last updated 2026-04-14 05:38:54; freshness should be verified.

Geography

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