miR-30d-5p in Type 1 Diabetes: Beta Cell and Immune Response Study Data

Data Sheet 1 from a figshare-hosted research article by Laia Gomez-Muñoz, last updated in June 2026. The 1.1 MB PDF contains data and results from a study investigating the role of microRNA miR-30d-5p in promoting beta cell recovery and immune regulation during the partial remission phase of type 1 diabetes. The study used human pancreatic slices, non-obese diabetic mice, and human peripheral blood samples.

Use Cases

• Analyzing transcriptional changes in beta cell function pathways based on RNA sequencing results mentioned in the description
• Investigating the association between miR-30d-5p and immune checkpoint molecule expression (e.g., PD-1, CTLA-4) in T cells
• Studying the effects of a specific miRNA on insulin secretion and beta cell lineage tracing in a human pancreatic slice model
• Evaluating potential therapeutic miRNA effects on diabetes onset delay in a mouse model

Strengths

• Data is associated with a specific, peer-reviewed research hypothesis on miR-30d-5p.
• Study employs multiple model systems: human pancreatic slices, NOD mice, and human T cells.
• Results include functional assays for insulin secretion and immune cell phenotyping.

Limitations

• The dataset is a 1.1 MB PDF; underlying raw data tables or sequences are not directly accessible.
• Row and column counts are unknown, limiting suitability assessment for computational analysis.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

figshare, author Laia Gomez-Muñoz

Collection Method

Experimental data from human pancreatic slice transfection, RNA sequencing, NOD mouse studies, and human T cell assays.

Freshness

Last updated 2026-06-02 04:21:26; freshness should be verified.