Mouse TAPBPR MHC-I Immunopeptidome Data Sheet

A 1.5 MB PDF data sheet from figshare, authored by Juliana Bernardi Aggio and last updated in April 2026. It characterizes mouse TAPBPR, a peptide exchange catalyst for Major Histocompatibility Complex class I, comparing its function to the human counterpart in shaping the presented peptide repertoire.

Use Cases

• Compare mouse and human TAPBPR function based on described binding and peptide selection experiments.
• Analyze peptide repertoire restriction on H2-Db and H2-Kb alleles based on findings from MC-38 cells.
• Investigate the selection of peptides with C-terminal methionine on H2-Kb promoted by mouse TAPBPR.
• Study MHC-I peptide loading catalysis in the presence of high-affinity peptides as described.

Strengths

• Data sheet is 1.5 MB in size.
• Released under a CC-BY-4.0 license for open reuse.
• Last updated on 2026-04-15, indicating recent availability.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Juliana Bernardi Aggio.

Collection Method

Experimental characterization of mouse TAPBPR in cell lines, as described.

Time Range

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Freshness

Last updated 2026-04-15 04:21:54.

Geography

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