AHL Quorum Sensing Data from Underexplored Bacterial Lineages

A 75.6 KB Excel file published on figshare by Christy R. Handel in May 2026. The dataset contains findings on N-acyl homoserine lactone-based quorum sensing systems in environmental bacteria, including two newly described Pseudomonadota species and two Gram-positive Actinomycetota strains. Analyses include genomic context, protein phylogeny, and mass spectrometry results for AHL production.

Use Cases

• Comparative genomic analysis of luxI/R homologs based on the described hidden Markov model searches.
• Phylogenetic study of LuxR-family protein domain architecture divergence from canonical systems.
• Investigating the ecological role of AHL signaling in underexplored microbial lineages and environments mentioned in the description.

Strengths

• Data is associated with a specific scientific publication, providing methodological context.
• Includes results from targeted gene disruption experiments in Rhodococcus kroppenstedtii Y88A.
• Analyses combine multiple techniques: custom HMMs, phylogenetics, and LC-MRM-MS.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (75.6 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Custom hidden Markov models, genomic context analysis, protein phylogeny, and liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS).

Freshness

Last updated 2026-05-08 17:27:23; freshness should be verified.

Geography

Samples from Hawai‘i (taro lo‘i, lava cave) and San Salvador Island, Bahamas (hypersaline mat).