N-acyl-homoserine Lactone Quorum Sensing Data from Underexplored Bacterial Lineages

A 75.6 KB Excel dataset from figshare details the investigation of N-acyl-homoserine lactone-based quorum sensing in underexplored bacterial lineages. Author Christy R. Handel published findings on April 20, 2026, expanding known diversity beyond the canonical Pseudomonadota model. The data likely contains results from genomic analyses, LC-MRM-MS assays, and targeted gene disruption experiments.

Use Cases

• Phylogenetic analysis of luxI/R-family protein divergence based on the described protein phylogeny.
• Comparative genomics to study gene context and architecture based on the mention of genomic context and domain analysis.
• Modeling regulatory frameworks for AHL signaling in Actinomycetota based on the described distinct evolutionary architectures.
• Training classifiers to identify putative quorum-sensing homologs based on the use of custom hidden Markov models (HMMs).

Strengths

• Includes data from four specific bacterial strains, including two newly described species.
• Combines multiple analysis methods: HMMs, phylogenetics, LC-MRM-MS, and gene disruption.
• Licensed under CC-BY-4.0 for open reuse and redistribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 75.6 KB file size suggests a limited scope of data points.

Provenance

Source

figshare

Collection Method

Custom HMMs, genomic context analysis, phylogenetics, LC-MRM-MS, and targeted gene disruption.

Time Range

null

Freshness

Last updated 2026-04-20 05:20:49; freshness should be verified.

Geography

Samples from Hawai‘i and San Salvador Island, Bahamas.