HPV E6/E7 mRNA Genotyping in China: 11,118 Women Across Seven Regions

Shengyang Xu published a dataset on figshare in April 2026. It contains results from a retrospective cross-sectional study analyzing 11,118 female cervical specimens for transcriptionally active high-risk HPV genotypes. The data covers seven geographic regions in China and includes genotype distribution, co-detection patterns, and multivariable logistic regression results.

Use Cases

• Analyze age-related heterogeneity in HPV52, HPV58, and HPV16 positivity based on the age group analysis described.
• Compare regional prevalence rates for high-risk HPV genotypes based on the geographic region data from seven areas.
• Study patterns of multi-type HPV co-detection based on the co-detection analysis mentioned in the results.
• Evaluate associations between testing context proxy categories and HPV positivity based on the multivariable logistic regression findings.

Strengths

• Dataset includes 11,118 samples, providing a substantial sample size.
• Analysis covers seven geographic regions in China, offering nationwide geographic coverage.
• Genotyping assay detected 14 high-risk HPV genotypes, including dominant types HPV52, HPV58, and HPV16.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic and temporal bias inherent to the specific collection period and institutions.

Provenance

Source

figshare

Collection Method

Retrospective cross-sectional study of cervical specimens retrieved for HPV E6/E7 mRNA testing.

Time Range

Specimens were collected between August 14, 2024 and October 23, 2025.

Freshness

Last updated 2026-04-24 05:39:56; freshness should be verified.

Geography

Seven geographic regions of China.