Neural Correlates of Loss Aversion in Alcohol Use Disorder from FDG-PET Imaging

22 AUD patients and 19 matched healthy controls performed a gambling task to measure loss aversion, with 18F-FDG-PET imaging used to investigate neural correlates in the AUD sample against 42 matched PET controls. The dataset, authored by Maria Arioli and last updated in May 2026, provides preliminary evidence of sex-related differences in the brain metabolism associated with altered decision-making. It is shared under a CC-BY-4.0 license as a 219.3 KB PDF file on figshare.

Use Cases

• Investigating the relationship between loss aversion and brain metabolism in clinical populations based on the described FDG-PET imaging.
• Analyzing sex-specific neural correlates of decision-making deficits based on the described findings of differential frontomedial metabolism.
• Studying the role of the salience network (anterior cingulate, anterior insula) in addiction based on the described hypometabolic patterns.
• Comparing behavioral task performance (gambling task) between clinical and control groups based on the described participant cohorts.

Strengths

• Includes data from 22 AUD patients, 19 matched behavioral controls, and 42 matched PET imaging controls, providing a multi-group comparison.
• Links behavioral measures (loss aversion from a gambling task) with neuroimaging data (18F-FDG-PET), enabling multimodal analysis.
• Explicitly investigates and reports preliminary evidence for sex-related differences in neural correlates.

Limitations

• The dataset is described in a 219.3 KB PDF file; the underlying raw data and column-level documentation are unavailable.
• The sample size is relatively small, which may limit the generalizability of the findings.
• Row count and specific data structure are unknown, requiring manual inspection after download.

Provenance

Source

figshare

Collection Method

Data was collected via a gambling task and 18F-FDG-PET imaging from clinical and control cohorts.

Freshness

Last updated 2026-05-13 05:51:58