Neuro-sensitization in Cats with Chronic Pain and Osteoarthritis

A prospective, negatively controlled study of 131 cats (10 healthy, 121 with naturally occurring osteoarthritis) enrolled to assess somatosensory neuro-sensitization. The dataset includes outcomes from quantitative sensory testing and a validated arthritis assessment instrument. It was authored by Manuela Lefort-Holguin and shared under a CC-BY-4.0 license on figshare.

Use Cases

• Modeling the relationship between peripheral sensitization (Paw Withdrawal Threshold) and osteoarthritis pain severity clusters.
• Comparing spinal sensitization (Response to Mechanical Temporal Summation) across different allodynia statuses (healthy, non-allodynic, allodynic).
• Investigating the influence of demographic factors like age and body weight on pain phenotype categorization.
• Validating the Montreal Instrument for Cat Arthritis Testing for Veterinarians (MI-CAT(V)) against quantitative sensory measures.

Strengths

• Includes data from 131 cats, providing a substantial sample for a veterinary clinical study.
• Uses validated instruments (MI-CAT(V)) and standardized quantitative sensory testing (PWT, RMTS).
• Employs a prospective, negatively controlled study design with clearly defined OA severity clusters.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (82.4 KB), indicating limited scope.

Provenance

Source

Manuela Lefort-Holguin

Collection Method

Prospective, negatively controlled clinical study.

Freshness

Last updated 2026-05-26 06:02:07; freshness should be verified.