Neurological Manifestations in Critically Ill COVID-19 Patients: A Sub-analysis Protocol

A pre-planned secondary analysis of the international COVID-19 Critical Care Consortium observational study, which collected data from the beginning of the pandemic. The dataset, authored by Denise Battaglini, is a protocol document describing the study design for analyzing neurological complications in adult COVID-19 patients admitted to the ICU. The protocol aims to assess incidence, risk factors, and outcomes, with data collected at ICU discharge and at 28 days.

Use Cases

• Assessing risk factors for neurological complications based on patient pre-admission characteristics and comorbidities mentioned in the description.
• Modeling associations between neurological complications and fatal outcomes based on in-hospital mortality data.
• Analyzing the type and severity of neurological complications in critically ill patients as described in the study protocol.

Strengths

• Data collection spans from the beginning of the COVID-19 pandemic, providing a relevant temporal scope.
• The study is international and multicenter, likely incorporating diverse patient populations.
• The protocol includes specific outcome measures such as in-hospital mortality and neurological status at 28 days.

Limitations

• The provided file is a 37.3 KB protocol document (DOCX), not the underlying dataset, which limits immediate analysis.
• Row count and column-level documentation for the actual data are unknown, requiring further investigation.
• Description metadata is limited; actual data quality requires manual inspection after obtaining the full consortium dataset.

Provenance

Source

COVID-19 Critical Care Consortium observational study.

Collection Method

Retrospective and prospective data collection from participating ICU sites.

Time Range

From the beginning of the COVID-19 pandemic.

Freshness

Last updated 2026-05-01 12:30:05; freshness should be verified.

Geography

International (multicenter).