Data Sheet 1_Neuroprotective effects of telmisartan in a harmaline-induced model of essent

A 640.1 KB PDF document authored by Sama M. Farrag and last updated on 2026-05-26. It describes a study investigating the neuroprotective effects of Telmisartan in a harmaline-induced rat model of essential tremor, analyzing behavioral, molecular, and immunohistochemical outcomes.

Use Cases

• Analyzing the effects of angiotensin receptor blockers on tremor severity based on behavioral tests described in the study.
• Studying the modulation of the renin-angiotensin system in cerebellar neurodegeneration based on molecular analysis of receptor expression.
• Investigating the link between neuroinflammation and essential tremor based on cytokine and signaling pathway data.
• Evaluating the restoration of excitatory/inhibitory neurotransmitter balance in animal models based on GABA and glutamate level analysis.

Strengths

• The study includes a detailed multi-modal analysis covering behavioral tests (rotarod, footprint, open field), molecular assays (receptor expression, cytokine levels), and immunohistochemistry.
• The dataset is openly licensed under CC-BY-4.0, allowing for reuse and redistribution.

Limitations

• The dataset is a single 640.1 KB PDF document, which is a very small-scale research report rather than a structured data collection.
• Column-level documentation is absent; field semantics must be inferred from the narrative text after download.
• The data is derived from a specific animal model study, which may limit direct applicability to human clinical contexts.

Provenance

Source

Sama M. Farrag via figshare

Collection Method

Experimental study involving male rats assigned to control, harmaline-induced, and telmisartan-treated groups.

Freshness

Last updated 2026-05-26 08:44:04; freshness should be verified.