First-Trimester Aldosterone and Hypertensive Disorders of Pregnancy Risk in China

A prospective cohort study of 1,486 pregnant women recruited from six hospitals in China between May 1, 2023, and December 31, 2024. The dataset likely contains clinical measurements, including first-trimester plasma aldosterone concentration (PAC), used to assess its nonlinear association with hypertensive disorders of pregnancy (HDP). The research was authored by Nanfang Li and shared under a CC-BY-4.0 license.

Use Cases

• Modeling nonlinear risk relationships based on biomarker thresholds described in the study
• Training predictive models for hypertensive disorders of pregnancy using first-trimester clinical data
• Conducting sensitivity analyses on clinical cohort data as demonstrated in the methodology

Strengths

• Dataset is based on a multicenter prospective cohort of 1,486 participants
• Specific statistical findings are reported, including a threshold effect at 39.30 ng/dL and an adjusted odds ratio of 0.962 below that threshold

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is small at 95.7 KB, indicating limited scope

Provenance

Source

figshare

Collection Method

Prospective, multicenter cohort study recruiting pregnant women from six hospitals in China.

Time Range

May 1, 2023 to December 31, 2024

Freshness

Last updated 2026-05-25 04:34:51; freshness should be verified

Geography

China