Olink Proteomics Data for Acupuncture Treatment of Mild Depression in Young Females

Data Sheet 1 presents Olink proteomics data from a clinical study investigating inflammatory biomarkers in young females with mild depression. The dataset includes plasma protein expression levels from 30 participants across healthy control, mild depression, and acupuncture treatment groups, analyzed using the Olink Target 96 Inflammation panel. The study was authored by Zhongxian Li and last updated on 2026-03 17.

Use Cases

• Identify differentially expressed plasma proteins based on Olink proteomics data mentioned in the description
• Validate treatment-responsive biomarkers like FGF-19 based on ELISA validation results described
• Explore correlations between protein expression and clinical depression scores (HAMD-17, SDS) referenced in the study

Strengths

• Includes validation from an expanded cohort of 40 participants per group using ELISA
• Clinical trial is registered with identifier ChiCTR2300068054, providing a traceable source
• Analysis includes Gene Ontology (GO) and KEGG pathway enrichment for biological interpretation

Limitations

• Dataset size is 95.1 KB, indicating a very limited scope and likely summary-level data
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare, author Zhongxian Li

Collection Method

Plasma samples analyzed via Olink Target 96 Inflammation panel from a controlled clinical trial

Time Range

Clinical trial registration identifier ChiCTR2300068054 suggests a 2023 study period

Freshness

Last updated 2026-03-17 13:05:37

Geography

Likely China, based on the Chinese Clinical Trial Registry identifier