Clinical Trial Data on Oral Prophylaxis for Reducing Pathogens During Pregnancy in Senegal

A randomized clinical trial conducted in six obstetric clinics in Senegal between March 2022 and January 2023. The dataset contains results from a study of 100 pregnant women evaluating the effect of interdental brushing on reducing bacterial loads of key periodontal pathogens. The study was authored by Florence Carrouel and shared under a CC-BY-4.0 license.

Use Cases

• Analyzing the efficacy of interdental cleaning interventions based on the described bacterial load reduction outcomes.
• Modeling the relationship between specific pathogen reduction and pregnancy health based on the trial's measured results.
• Benchmarking oral hygiene protocols in prenatal care based on the statistically significant reductions reported for T. denticola.
• Studying geographic or demographic factors in oral health interventions based on the trial's setting in Senegal.

Strengths

• Data originates from a randomized controlled trial, a robust study design for causal inference.
• Results include specific, quantified reductions in bacterial load, such as a 36.6% mean total reduction and a 92.1% reduction for T. denticola.
• Clear temporal coverage from the third to eighth month of pregnancy for 100 participants.

Limitations

• The dataset is a 918.8 KB DOCX document; the underlying structured data (e.g., column-level records) is not directly accessible.
• Row count and column-level documentation are unknown, which limits suitability assessment for direct computational analysis.
• The description notes that reductions for P. gingivalis and T. forsythia were not statistically significant (p=0.061 and p=0.148).

Provenance

Source

Florence Carrouel via figshare

Collection Method

Randomized controlled trial using real-time polymerase chain reaction (PCR) techniques.

Time Range

March 2022 to January 2023

Freshness

Last updated 2026-04-23 04:19:55; freshness should be verified.

Geography

Senegal