Oxygen Extraction Fraction Associations in Alzheimer's and Non-Alzheimer's Dementias

A study comparing 16 Alzheimer's disease and 15 non-Alzheimer's dementia patients. It quantifies oxygen extraction fraction in cortical and deep gray matter regions using an MRI-based technique and analyzes its association with white matter hyperintensities and cognitive impairment. The dataset was authored by Arpita Misra and last updated on April 28, 2026.

Use Cases

• Train models to differentiate Alzheimer's from non-Alzheimer's dementias based on oxygen extraction fraction patterns.
• Analyze the relationship between tissue oxygen usage and white matter hyperintensities in dementia patients.
• Investigate associations between oxygen extraction fraction and cognitive impairment scores measured by the Montreal Cognitive Assessment.

Strengths

• Includes data from 31 total patients (16 AD, 15 non-AD), providing a comparative cohort.
• Focuses on a novel MRI-based OEF mapping technique (QQ), offering a specific methodological detail.
• License is CC-BY-4.0, permitting broad reuse and sharing.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The primary data file is a 2.0 MB DOCX document, which may not be a standard format for structured data analysis.

Provenance

Source

figshare

Collection Method

Data was gathered using a novel MRI-based OEF mapping technique (QQ) on patient cohorts.

Freshness

Last updated 2026-04-28 05:28:11; freshness should be verified.