Bacillus Cereus Pathogenesis Data from Galleria Mellonella Infection Model

A 77.6 KB Excel dataset by Jessica Minnaard, uploaded to figshare on April 15, 2026. It contains results from a study using the insect Galleria mellonella to model human infection by two Bacillus cereus strains (T1 and B10502) from food poisoning outbreaks. The data likely includes genomic comparisons, larval survival rates, bacterial persistence, and immune response markers like phenoloxidase activity.

Use Cases

• Comparative genomic analysis of virulence factors based on the described presence of Nhe complex, hemolysins, and phospholipase genes.
• Modeling dose-dependent mortality and bacterial persistence in hosts based on larval infection assay results.
• Analyzing correlations between specific genetic differences (e.g., hblABCD complex) and observed immune response markers like melanization and hemocyte viability.

Strengths

• Data is derived from a controlled experimental model combining genomic analysis with in vivo infection assays.
• Focuses on two distinct B. cereus strains with documented differences in virulence toward human cells.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and specific column definitions are unknown, requiring manual inspection after download.
• The dataset is very small (77.6 KB), indicating limited scope and likely a focused experimental result set.
• Column-level documentation is absent; field semantics must be inferred from the description.

Provenance

Source

Jessica Minnaard via figshare.

Collection Method

Combined genomic analysis with Galleria mellonella larval infection assays, measuring survival, bacterial persistence, immune activation, and spore formation.

Time Range

Experimental timeframe not specified; dataset metadata updated in 2026.

Freshness

Last updated 2026-04 05:23:05.

Geography

Not specified; likely from a laboratory study.