Rectal Cancer Pathologic Response Data from a Vietnamese Study

A prospective study from Vietnam enrolled 101 patients with stage II–III rectal cancer to evaluate total neoadjuvant therapy. The dataset includes pathologic response outcomes, with 95 patients undergoing resection and a pathological complete response rate of 35.7%. It contains clinical variables related to treatment regimens, tumor regression, and safety outcomes.

Use Cases

• Analyze the relationship between treatment regimen (CAPOX or FOLFOX) and pathologic complete response rate.
• Model predictors of good tumor regression grade (TRG 0–1) using patient clinical and treatment data.
• Assess treatment completion rates and toxicity profiles across the patient cohort.
• Compare pathologic response outcomes from this Vietnamese center to global benchmarks for locally advanced rectal cancer.

Strengths

• Prospective study design with a defined cohort of 101 enrolled patients.
• Reports specific clinical outcomes, including a 35.7% pathological complete response rate among 95 resected patients.
• Clear focus on a resource-limited setting (Vietnam), providing data often underrepresented in global research.

Limitations

• Small sample size of 101 patients limits statistical power for subgroup analyses.
• Single-arm, single-center study design may limit generalizability to other populations or healthcare systems.
• The dataset is very small (32.8 KB), indicating limited scope and number of variables.

Provenance

Source

Vo Duc Hieu, via figshare.

Collection Method

Prospective single-arm study conducted at a Vietnamese oncology center.

Time Range

null

Freshness

Last updated March 2026.

Geography

Vietnam.