Percutaneous Coronary Intervention Outcomes in Patients Under 40

Lining Liang's single-center cohort study analyzes 312 consecutive patients aged ≤40 years who underwent successful percutaneous coronary intervention (PCI) between 2014 and 2024. It tracks major adverse cardiovascular and cerebrovascular events (MACCE) over 1,620 patient-years, with a median follow-up of 5.2 years. The study identifies independent predictors of MACCE, including diabetes, SYNTAX score, and dual antiplatelet therapy duration.

Use Cases

• Analyze the association between SYNTAX score and major adverse cardiovascular and cerebrovascular events (MACCE) rates in young PCI patients.
• Model the impact of diabetes status and dual antiplatelet therapy duration on long-term cardiac mortality risk.
• Examine procedural patterns, such as radial access and drug-eluting stent implantation rates, in this very young patient cohort.

Strengths

• Study includes 312 consecutive patients, providing a focused cohort of a specific demographic.
• Long-term follow-up over 1,620 patient-years with a median of 5.2 years per patient.
• Identifies statistically significant predictors (e.g., diabetes, SYNTAX score) with reported hazard ratios and confidence intervals.

Limitations

• Single-center retrospective design limits generalizability of findings to other populations.
• Small dataset at 15.3 KB, indicating the primary data is likely a summary or document, not a detailed patient-level database.
• Patient cohort is 82% men, indicating a potential gender imbalance in the sample.

Provenance

Source

Lining Liang via figshare.

Collection Method

Single-center retrospective cohort study of consecutive patients.

Time Range

Procedures performed between 2014 and 2024.

Freshness

Data covers procedures from 2014 to 2024, with the record last updated in March 2026.

Geography

Single-center study; specific location not stated.