Norovirus Persistence in Simulated Gastrointestinal Digestion Experiments

Human and murine norovirus persistence was measured during simulated digestion using static INFOGEST and dynamic TIM-1 models. The 875 KB dataset likely contains experimental results for viruses suspended in water or mixed with raspberries, strawberries, lettuce, or oysters. Rosie Beaulieu published the data on figshare under CC-BY-4.0 license.

Use Cases

• Compare virus persistence between static and dynamic digestion models based on the INFOGEST and TIM-1 simulators mentioned.
• Analyze the impact of different food matrices on norovirus survival based on tests with raspberries, strawberries, lettuce, and oysters.
• Validate PMAxx-RT-qPCR as a proxy for intact viral particles based on the described assessment method.
• Model the risk of norovirus transmission via the fecal-oral route based on persistence data from simulated gastrointestinal transit.

Strengths

• Data compares two complementary in vitro digestion models: static INFOGEST and dynamic TIM-1.
• Experiments include high-risk food matrices like raspberries, strawberries, lettuce, and oysters.
• Virus persistence was assessed using both plaque assays for MNV-1 and PMAxx-RT-qPCR for HuNoV.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is 875 KB, indicating a limited scope of experimental results.

Provenance

Source

figshare

Collection Method

Experimental data from simulated gastrointestinal digestion studies.

Freshness

Last updated 2026-03-19 06:50:05; freshness should be verified.