Case Report on Personalized Management of GCK-MODY Diabetes During Pregnancy

A 3.4 MB PDF case report authored by Ana Filipa Bolas, published on figshare under a CC-BY-4.0 license and last updated in May 2026. It details the management of a 33-year-old woman with glucokinase-related monogenic diabetes (GCK-MODY) during her pregnancy, including the use of continuous glucose monitoring and intensive insulin therapy.

Use Cases

• Study clinical decision-making for diabetes in pregnancy based on the described case of a variant of uncertain significance.
• Analyze the application of continuous glucose monitoring (CGM) for glycemic control in a prenatal setting as detailed in the report.
• Review the role of intensive insulin therapy regimens, including basal-bolus administration, for managing GCK-MODY during pregnancy.
• Examine the impact of shared decision-making and multidisciplinary approaches in complex prenatal care scenarios.

Strengths

• The report provides a detailed, longitudinal clinical narrative of a single patient case.
• It includes specific clinical data points such as HbA1c levels (6.5% to 6.8%), genetic variant details (NM_000162.5:c.829_830insCGG), and neonatal outcomes (2970g, APGAR scores).

Limitations

• The dataset is a single case report, limiting statistical generalizability and scale.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Clinical case documentation.

Freshness

Last updated 2026-05-28 04:52:42; freshness should be verified.