Data Sheet 1_Phenotype-driven protocol switching is associated with improved ART outcomes

Jie Gao authored a retrospective study analyzing 4,632 consecutive assisted reproductive technology cycles from January 2010 to December 2025. The research evaluates the impact of phenotype-driven protocol switching on cumulative live birth rates while keeping gonadotropin dosages constant. The dataset underpinning this analysis is available under a CC-BY-4.0 license.

Use Cases

• Compare cumulative live birth rates between different ART protocol strategies based on the described patient pathways.
• Analyze the relationship between oocyte retrieval numbers and protocol switches like Long-to-Antagonist.
• Investigate predictors of good embryo rate improvement following specific protocol changes, such as Antagonist-to-Mild.
• Model the effect of age and anti-Müllerian hormone on ART outcomes while controlling for protocol strategy.

Strengths

• Dataset is based on a large-scale study of 4,632 patient cycles.
• Analysis covers a 15-year time range from 2010 to 2025.
• Study design is self-controlled, comparing consecutive cycles for the same patients.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying data is unknown, which may limit suitability assessment.
• Data may reflect temporal and source bias inherent to the single retrospective study.

Provenance

Source

figshare

Collection Method

Retrospective, self-controlled clinical study.

Time Range

January 2010 to December 2025

Freshness

Last updated 2026-05-13 04:41:26; freshness should be verified.